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- Hermione Gulliford as Roxanna MacMillan
- Paul McGann as John Gaskell
- Marcus Griffiths as Xavier "Zav" Duval
- Belinda Owusu as Nicky McKendrick
- Salma Hoque as Meena Chowdhury
- David Ames as Dominic Copeland
- Jaye Jacobs as Donna Jackson
- Lee Mead as Ben "Lofty" Chiltern
- Rosie Marcel as Jac Naylor
- Alex Walkinshaw as Adrian "Fletch" Fletcher
- Hugh Quarshie as Ric Griffin
- Bob Barrett as Sacha Levy
- Catherine Russell as Serena Campbell
- Wanda Ventham as Sheilagh Chiltern
- Olivia Poulet as Abigail Tate
- Helen Belbin as Maria Lambourne
- Nathan Osgood as Leo Haywood
- Alhaji Fofana as Jackson "Jacks" Williams
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