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- Hermione Guilliford as Roxanna MacMillan
- Guy Henry as Henrik Hanssen
- Paul McGann as John Gaskell
- Kaye Wragg as Essie Di Lucca
- Salma Hoque as Meena Chowdhury
- Hugh Quarshie as Ric Griffin
- Bob Barrett as Sacha Levy
- David Ames as Dominic Copeland
- Lee Mead as Ben 'Lofty' Chiltern
- Catherine Russell as Serena Campbell
- Belinda Owusu as Nicky McKendrick
- Jaye Jacobs as Donna Jackson
- Alex Walkinshaw as Adrian "Fletch" Fletcher
- Rosie Marcel as Jac Naylor
- Olga Fedori as Frieda Petrenko
- Jesse Birdsall as Steven Fletcher
- Hannah Daniel as Leah Faulkner
- Hiran Abeysekera as Tyler Saba
- Ciaran Kellgren as Lyle Laidlow
- Angela Lonsdale as "Scary" Sue Buchanan
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