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- Hermione Gulliford as Roxanna MacMillan
- Paul McGann as John Gaskell
- Olga Fedori as Frieda Petrenko
- Belinda Owusu as Nicky McKendrick
- Salma Hoque as Meena Chowdhury
- Alex Walkinshaw as Adrian "Fletch" Fletcher
- Rosie Marcel as Jac Naylor
- David Ames as Dominic Copeland
- Lee Mead as Ben "Lofty" Chiltern
- James Anderson as Oliver Valentine
- Jaye Jacobs as Donna Jackson
- Catherine Russell as Serena Campbell
- Hugh Quarshie as Ric Griffin
- Guy Henry as Henrik Hanssen
- Macey Chipping as Evie Fletcher
- Zoe Croft as Greta Allinson
- Jules Robertson as Jason Haynes
- Rob Witcomb as Curtis Langford
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