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- Paul McGann as John Gaskell
- Salma Hoque as Meena Chowdhury
- Rosie Marcel as Jac Naylor
- Catherine Russell as Serena Campbell
- Jaye Jacobs as Donna Jackson
- Lee Mead as Ben "Lofty" Chiltern
- Hermione Gulliford as Roxanna MacMillan
- Alex Walkinshaw as Adrian "Fletch" Fletcher
- Bob Barrett as Sacha Levy
- Belinda Owusu as Nicky McKendrick
- Guy Henry as Henrik Hanssen
- Hugh Quarshie as Ric Griffin
- Zoe Croft as Greta Allinson
- Olivia Poulet as Abigail Tate
- Jules Robertson as Jason Haynes
- Jemma Redgrave as Bernie Wolfe
- Wela Mbusi as Philippe Duplessis
- Debbie Chazen as Fleur Fanshawe
- Walles Hamonde as Driss Aloui
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