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Series 10 of Holby City commenced on 16 October 2007 and finished on 14 October 2008; it comprised 53 episodes.
Cast
Main characters
- Hugh Quarshie as Ric Griffin
- Amanda Mealing as Connie Beauchamp
- Sharon D Clarke as Lola Griffin
- Adrian Edmondson as Percy "Abra" Durant
- Paul Bradley as Elliot Hope
- Peter Wingfield as Dan Clifford
- Hari Dhillon as Michael Spence
- Duncan Pow as Linden Cullen
- Rosie Marcel as Jac Naylor
- Tom Chambers as Sam Strachan
- Luke Roberts as Joseph Byrne
- Nadine Lewington as Maddy Young
- Robert Powell as Mark Williams
- Tina Hobley as Chrissie Williams
- Rakie Ayola as Kyla Tyson
- Patsy Kensit as Faye Morton
- Phoebe Thomas as Maria Kendall
- Rebecca Grant as Daisha Anderson
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| Series 9 | Series 11 |