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Charlie, recovering from his pulmonary embolism meets a young mother and her baby, Phoenix. When the mother tries to commit suicide, Charlie springs into action, doing just what he knows best. Return of Spencer and arrival of Senior Staff Nurse Colette Kierney.
The press have found out about Adam – He's HIV positive. Can the staff convince the public there's nothing to fear, or is it curtains for Adam's career as an A&E Nurse?
Josh has been caught in a mudslide and Adam decides to make a statement to the press. Deciding to quit, Adam and Reuben get married and drive off to the sound of salsa. Meanwhile, Leona is back in the department. Final appearances of Staff Nurse Adam Osman and Reuben Hurst
Andrew Bower , Duffy's husband has returned to the department following Broadway General's closure. Can Duffy pull herself together and be able to work amicably with Andrew or are the couple heading for a fall?
Holly has taken Patrick to a christmas meal but is met with snide remarks and sarcasm from the ever moody registrar. On the way back to the department for their shifts, Patrick's car breaks down in the snow and the two medics are forced to seek shelter in a disused barn where more than a few secrets are going to be told.
Patrick and Spencer are taken hostage by an ex-navy officer who doesn't want his daughter to see one of Spencer's old shipmates. Will Holly be able to figure out Patrick's coded message and save them before it's too late?
Josh, Fin, Barney and Tom have only one thing in mind – they must transfer a critical burns patient to another hospital before he dies of his injuries. Little do they expect a teenager to try to flag them down on their way...
Tom has finally achieved his goal. He's got Holly alone with him in his house. Can Dan figure out the truth behind Holly's mysterious stalker and save her before it's too late?
Tom has been released on conditional bail and makes a beeline for A&E. When Holly hears her car alarm going off, she goes outside to investigate – discovering that the glass has been smashed and Tom is right behind her...
Tom has kidnapped Holly and is holding her in a disused area of the hospital. Elsewhere Patrick, Dan and Spencer work together to save Holly but Andrew proves to be the biggest casualty of the night...Final appearances of Anaesthetist Tom Harvey, Locum Consultant Andrew Bower, Staff Nurse Barney Woolfe, Paramedics Penny Hutchens and Melanie Dyson, Directorate Manager Dan Robinson and SHO Holly Miles.
