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Series 16 of Holby City commenced on 15 October 2013 and finished on 7 October 2014; it comprised 52 episodes.
Cast[]
Main characters[]
- Catherine Russell as Serena Campbell
- John Michie as Guy Self (from episode 7)
- Hugh Quarshie as Ric Griffin
- Paul Bradley as Elliot Hope
- Hari Dhillon as Michael Spence (until episode 10)
- Rosie Marcel as Jac Naylor
- Jimmy Akingbola as Antoine Malick (until episode 7)
- Aden Gillett as Edward Campbell (until episode 13)
- Bob Barrett as Sacha Levy
- Chizzy Akudolu as Mo Effanga
- Joe McFadden as Raffaello Di Lucca (from episode 16)
- Jules Knight as Harry Tressler
- Rob Ostlere as Arthur Digby
- Ty Glaser as Gemma Wilde (until episode 10)
- Camilla Arfwedson as Zosia March
- David Ames as Dominic Copeland (from episode 14)
- Louise Delamere as Colette Sheward (from episode 8)
- Tina Hobley as Chrissie Williams (until episode 6)
- Michael Thomson as Jonny Maconie
- Alex Walkinshaw as Adrian Fletcher (from episode 44)
- Niamh McGrady as Mary-Claire Carter
- Lauren Drummond as Chantelle Lane (until episode 5)
- Petra Letang as Adele Effanga (from episode 14)
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