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Series 18 of Holby City aired between 13 October 2015 and 4 October 2016. This series comprised 52 episodes.
Cast
Main characters
- Guy Henry as Henrik Hanssen
- Catherine Russell as Serena Campbell
- Hugh Quarshie as Ric Griffin
- Rosie Marcel as Jac Naylor
- John Michie as Guy Self
- Don Gilét as Jesse Law
- Jemma Redgrave as Bernie Wolfe (From Episode 17)
- Bob Barrett as Sacha Levy
- James Anderson as Oliver Valentine
- Chizzy Akudolu as Mo Effanga
- Joe McFadden as Raffaello Di Lucca
- Rob Ostlere as Arthur Digby
- David Ames as Dominic Copeland
- Camilla Arfwedson as Zosia March
- Eleanor Fanyinka as Morven Shreve
- Lucinda Dryzek as Jasmine Burrows
- Alex Walkinshaw as Adrian "Fletch" Fletcher
- Kaye Wragg as Essie Harrison
- Niamh Walsh as Cara Martinez
- Petra Letang as Adele Effanga
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