This article is not part of the Holby universe.
This article covers a subject that is part of the real world, and thus should not be taken as a part of the Holby universe.
Series 21 of Holby City commenced on 2 January 2019 and finished on 31 December 2019; it comprised 53 episodes.
Cast 
Edit
Main characters Edit
- Guy Henry as Henrik Hanssen (until episode 33)
- Catherine Russell as Serena Campbell
- Rosie Marcel as Jac Naylor
- Bob Barrett as Sacha Levy
- Dawn Steele as Ange Godard (from episode 2)
- Hugh Quarshie as Ric Griffin
- Ramin Karimloo as Kian Madani (from episode 17)
- Jo Martin as Max McGerry (from episode 42)
- Olga Fedori as Frieda Petrenko (until episode 13)
- Marcus Griffiths as Xavier "Zav" Duval
- David Ames as Dominic Copeland
- Amy Lennox as Chloe Godard (from episode 5)
- Belinda Owusu as Nicky McKendrick
- Nic Jackman as Cameron Dunn (from episode 1)
- Alex Walkinshaw as Adrian "Fletch" Fletcher
- Jaye Jacobs as Donna Jackson
- Kaye Wragg as Essie Di Lucca
- Lee Mead as Ben "Lofty" Chiltern (until episode 51)
Recurring characters Edit
- Jules Robertson as Jason Haynes
- Darcey Burke as Emma Naylor-Maconie
- Zoe Croft as Greta Allinson (until episode 1)
- Debbie Chazen as Fleur Fanshawe (until episode 47)
- Angela Lonsdale as "Scary" Sue Buchanan (until episode 27)
- Briana Shann as Mia Barron (until episode 15)
- Emma Curtis as Holly Cartwright (episodes 5 - 11)
- Emma Curtis as Holly Cartwright (episodes 5 - 11)
- Philip Whitchurch as Jim Mullins (episodes 5 - 9)
- Marianne Oldham as Ruth Cooper (episodes 6 - 11)
- Julia Deakin as Carole Copeland (from episode 7)
- Christopher Harper as Michael Cartwright (episodes 7 - 11)
- Camilla Arfwedson as Zosia March (episodes 8 - 16)
- Sirine Saba as Patricia Ghraoui (episodes 9 - 25)
- Naomi Katiyo as Darla Johnstone (episodes 10 - 41)
- Suzette Llewellyn as Nanette Duval (episodes 12 - 26)
- Jack Ryder as Evan Crowhurst (episodes 12 - 44)
- Daisy Wood-Davis as Phoebe Palmer (episodes 14 - 51)
- Marc Elliott as Isaac Mayfield (episodes 20 - 24)
- Geoffrey Leesley as Jon Mayfield (episodes 21 - 23)
- Harry Weston as Oskar Johansson (episodes 23 - 33)
- Verity Marshall as Helen Pidge (episodes 28 - 48)
- Sophie Harkness as Frankie Rendell (episodes 34 - 42)
- Rosalind Halstead as Beatrice "Bea" Kaminski (episodes 41 - 52)
- Paul Bradley as Elliot Hope (episodes 45 - 50)
- Charlie Condou as Ben Sherwood (from episode 52)
EpisodesEdit
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| Series 20 | Series 22 |
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