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Series 22 of Holby City commenced in January 2020. This series was initially set to comprise 52 episodes.

On 18 March 2020, the BBC announced that all filming for BBC Studios continuing dramas, including Holby City, had been postponed until further notice due to the spread of COVID-19. On 9 April, it was announced that the series would be going on an extended break, with the last episode airing on 14 April. The show returned on 2 June, however, the show is set to go on a further extended break from 11 August, and this is set to be longer than the first break, the show will return towards the end of 2020.


Main characters

Recurring characters

Guest characters


Episode No. Series No. Title Director(s) Writer(s) Original airdate
1009 1 Episode 1009 Jan Bauer Patrick Homes 7 January 2020
2201JacKianInMountains.png When a defeated Kian finds himself in a dark place, will Jac be able to pull him back from the edge? Meanwhile, a past acquaintance puts Max in a compromising position.
1010 2 Episode 1010 David Innes Edwards Katie Douglas 15 January 2020
2202JacKianReturn.png Jac and Kian return to work, but can they support each other and conquer their demons? Demoted and back in the trenches, Serena must find a role for herself. And will Sacha's efforts to help with Essie's home life only push her into Ben's arms for good?
1011 3 Episode 1011 David Innes Edwards Katie Douglas 21 January 2020
2203SerenaProtests.png With Jason's job in jeopardy, can Serena afford to put her neck on the line for her nephew? Tracey McKendrick brings trouble to Holby. How far will Nicky go to protect her mum? And can Essie trust boyfriend Ben enough to share the secret of baby Isla’s illegal adoption?
1012 4 Episode 1012 Dermot Boyd Davey Jones 28 January 2020
2204SachaWithMaria.png On Holocaust Memorial Day, Sacha's beloved great-aunt - a Holocaust survivor - is admitted in very poor health. Meanwhile, Cameron sees red while dealing with a stabbing victim.
1013 5 Episode 1013 Dermot Boyd Nick Fisher 5 February 2020
2205SachaInsistsOnOperating.png It’s the day of Sacha's groundbreaking transplant operation. As he is still overcoming a bereavement, Max wonders whether Sacha is fit to carry out the procedure. Meanwhile, Nicky’s woes escalate when Max finds out that she’s been moonlighting, and Donna has stars in her eyes when she meets a patient who happens to be a casting director.
1014 6 Episode 1014 Daikin Marsh Claire Miller 11 February 2020
2206CameronThreatensSteve.png It’s Valentine’s Day, but will Cupid’s arrow hit the target for Chloe and Cameron? Will Nicky risk a life to pay off a debt? A troubled Sacha is guided by the faith of an old friend.
1015 7 Episode 1015 Daikin Marsh Johanne McAndrew and Elliot Hope 18 February 2020
2207ZavConfrontsCameron.png It’s the morning after the night before, but will Cameron and Chloe reconcile? A familiar face waltzes back into Holby and ruffles a few feathers, and when Jac’s plans with Emma fall through, a colourful character comes to the rescue.
1016 8 Episode 1016 Waris Islam Alex Straker 25 February 2020
2208SachaEssie.png A galvanised Ric clashes with Max as he goes above and beyond for a patient. Essie has to choose between Ben and Sacha, and Kian returns from Canada determined to push Jac out of her comfort zone.
1017 9 Episode 1017 Waris Islam Damian Mullen 26 February 2020
2209MaxResistsDrinking.png Max finds herself in a desolate place after receiving distressing news, but following her fallout with Ric has she lost her closest confidante? Jac and Kian must decide who will be Darwin’s next clinical lead, but neither is quite ready to make the call.
1018 10 Episode 1018 Jamie Annett Isla Gray 10 March 2020
2210CameronExplainsLiftIncident.png Xavier unearths a shocking secret, and Fletch struggles to handle the nursing shortage. Reeling from recent revelations, Sacha, Essie, Dom and Ben peform life-saving surgery on a vulnerable child.
1019 11 Episode 1019 Jamie Annett Ed Sellek 24 March 2020
2211ZavConfrontsCameron.png With Xavier hot on his trail, how far will Cameron go to keep Evan dead and buried? Roger Ffolkes forces Ben to own his secrets.
1020 12 Episode 1020 Steve Brett Ed Sellek 31 March 2020
2212MaxMeetsLouis.png Max is feeling nervous at the thought of seeing her daughter again after years of estrangement. ED nurse David Hide joins the Darwin crew for the day, but Jac deems him not worthy. Essie waits for her routine cancer check-up, while Sacha encourages her to bury the hatchet with Dom.
1021 13 Episode 1021 Steve Brett Simon Norman 7 April 2020
2213SachaEssieEngaged.png Max struggles to come to terms with an explosive revelation. Jac and Kian bond over pizza and wine, and Dom tries to reason with a distraught Essie.
1022 14 Episode 1022 Griff Rowland Joe Ainsworth 14 April 2020
2214NickyHoldsZavsHeart.png As his disciplinary hearing begins, Xav is determined to prove that Cameron killed Evan. Essie faces the fight of her life as she undergoes her first round of chemotherapy.
1023 15 Episode 1023 Griff Rowland Becky Prestwich 2 June 2020
2215GuyReturns.png Essie’s friends try to keep things normal as she continues her chemotherapy. Jac and Kian’s relationship takes an unexpected turn, and can Guy keep his relationship under wraps?
1024 16 Episode 1024 Jennie Darnell Phil Mulryne 9 June 2020
2216EssieFletchConfide.png Essie puts on a brave face, but the effects of chemo start to take a toll. Guy has a lot to prove as he faces a challenging case on his first day on AAU, and Jac tries to keep things professional with Kian on the ward, but he has other ideas.
1025 17 Episode 1025 Jennie Darnell Johnny Candon 16 June 2020
2217Kian.png As things with Jac heat up, Kian is thrown off balance when a patient causes painful memories to resurface. Tensions run high as Louis adjusts to life in his mum’s hospital, and Guy tries to make amends for last week. Fletch puts his foot in it when he receives an unwanted gift.
1026 18 Episode 1026 David Innes Edwards Katie Douglas 23 June 2020
2218FletchTellsEvieHeHasCancer.png Fletch and his daughter Evie reveal life-changing secrets they have both been keeping, and what will Max do when dangerous truths are exposed on the biggest day of her career?
1027 19 Episode 1027 David Innes Edwards Katie Douglas 30 June 2020
2219EssieCries.png Cameron is gutted when his performance review doesn’t go to plan, and Nicky’s attempts to find a life-saving treatment for Brenda put her at odds with Jac. While staff fuss over Fletch as he recovers from surgery, Essie may know something that will change life on Keller forever.
1028 20 Episode 1028 Dean Byfield Julie Parsons 7 July 2020
2220LouisNicky.png Nicky struggles to cope at work as her world collapses around her. Cameron takes his pent-up anger out on an innocent Louis.
1029 21 Episode 1029 Dean Byfield Ed Sellek 14 July 2020
2221JacConfrontsNicky.png Nicky wakes up in hospital to find her overbearing mother interfering in both her work and personal life. She takes the opportunity to reassess her priorities. Fletch and Essie befriend a cancer patient, but the relationship forces all three of them to confront some ugly truths about what the future holds.
1030 22 Episode 1030 Karl Neilson Davey Jones 21 July 2020
2222EssieSeesRaf.png Ric suspects Guy has fallen off the wagon and sets out to stop him working at Holby, once and for all. Kian returns to Darwin Ward, determined to make amends with Jac. But when forgiveness doesn't come easy, Kian goes into self-destruct – with almost fatal consequences.
1031 23 Episode 1031 Karl Neilson Nick Fisher 28 July 2020
2223Drew.png Cameron fears new locum Drew is out to expose him, Kian spends the day babysitting Emma in order to win back Jac's heart, and how low will Sacha stoop to convince Essie?
1032 24 Episode 1032 Tracey Rooney Lucia Haynes 4 August 2020
2224GuysHearing.png Ric clashes with Max when his determination to destroy Guy puts his health at risk. Distressed by Frankie’s disappearance, Essie’s suspicions are raised when Sacha avoids the subject. Chloe struggles to keep things professional when her dating life spills onto the ward.
1033 25 Episode 1033 Tracey Rooney Joe Ainsworth 11 August 2020
2225GoodbyeMyLove.png Finding Ric unconscious in theatre, Guy capitalises on the unexpected opportunity. Sacha tries to make things right with Essie, and Nicky receives a surprising offer.
1034 26 Episode 1034 Steve Brett TBA 10 November 2020
HolbyCitySeries18TitleCard.png Ric wakes, after brain surgery, to find that the world around him has completely changed and that Holby is gripped by a coronavirus pandemic. What are Ric's chances of survival?
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