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- Amanda Mealing as Connie Beauchamp
- Hugh Quarshie as Ric Griffin
- Mark Moraghan as Owen Davis
- Art Malik as Zubin Khan (until episode 51)
- Ian Aspinall as Mubbs Hussein (until episode 52)
- Patricia Potter as Diane Lloyd
- Noah Huntley as Will Curtis (until episode 25)
- Sharon D Clarke as Lola Griffin (from episode 34)
- Adam Best as Matt Parker (from episode 29)
- Paul Henshall as Dean West (from episode 29)
- Tina Hobley as Chrissie Williams
- Luisa Bradshaw-White as Lisa Fox (until episode 48)
- Verona Joseph as Jess Griffin
- Sharon Maughan as Tricia Williams
- Kim Vithana as Rosie Sattar (until episode 13)
- Kelly Adams as Mickie Hendrie
- Jaye Jacobs as Donna Jackson
- Robert Powell as Mark Williams (from episode 18)
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