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- Peter Wingfield as Dan Clifford
- Tom Chambers as Sam Strachan
- Luke Roberts as Joseph Byrne
- Tina Hobley as Chrissie Williams
- Rakie Ayola as Kyla Tyson
- Rosie Marcel as Jac Naylor
- Sharon D Clarke as Lola Griffin
- Adam Best as Matt Parker
- Paul Bradley as Elliot Hope
- Phoebe Thomas as Maria Kendall
- Amanda Mealing as Connie Beauchamp
- Jaye Jacobs as Donna Jackson
- Patrick Toomey as Christopher Sutherland
- Adrian Edmondson as Percy "Abra" Durant
- Holly Lucas as Martha Hope
- Antonia Bernath as Nikki Brown
- Vanessa Ackerman as Zanna Malachi
- Liz Crowther as Iona Morrow
- Tony Turner as Myles Morrow
- Geff Francis as Kendall Braddock
- James Webber as Pharmacist
- Fiona Wade as Julianna McKenzie
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